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Evaluating T-cell engager therapy: Real-world insights from Osler
Posted on Monday, February 23, 2026 09:09 AM
Cancer treatment has evolved over time with recent advances expanding the options, including innovative approaches such as targeted therapies and immunotherapies. Immunotherapy now offers multiple modalities, including immune checkpoint inhibitors, chimeric antigen receptor (CAR) T-cell therapies and T-cell engagers, providing more precise and personalized alternatives for many patients.
T-cell engager therapies are transforming cancer care by harnessing the body’s immune system to target...
Financial hardship, chronic kidney disease, and the case for policy action in Canada
Posted on Monday, December 01, 2025 09:56 AM
Canada’s universal health care system is often held up as a safeguard against financial hardship caused by illness. Yet for many people living with chronic kidney disease (CKD), financial strain is a defining feature of their care journey. In the recently published article, Financial hardship amongst patients living with chronic kidney disease in Canada, a persistent, and largely invisible problem is highlighted: non-medical costs and income loss associated with CKD can profoundly shape health...
New study reveals path to better outcomes through faster, more accurate biomarker testing
Posted on Monday, April 21, 2025 01:49 PM
A landmark Canadian study is calling attention to urgent gaps in biomarker testing for non-small cell lung cancer, revealing a clear path to better patient outcomes and more equitable access to life-saving care across the country.
Published in JTO Clinical and Research Reports, the study was developed through the Canadian Pathology Quality Assurance end-to-end quality assurance (EQA) program. The Advanced Diagnostics team at Osler led this cross-disciplinary effort which examined biomarker...
How adaptive leadership can enhance health care ethics
Posted on Friday, April 04, 2025 01:54 PM
In today’s health care systems, ethical considerations are routinely addressed on a wide range of topics, from bedside decision-making to institutional policy. Ethicists are well integrated into health care teams and often use decision-making frameworks and strategies to support health professionals in navigating tough decisions.
A recent article published in the Healthcare Management Forum, by the ORIHI Ethics Quality Improvement Lab, challenges this traditional model, proposing that ethical...
Welcome 2025 summer student researchers
Posted on Tuesday, April 01, 2025 02:16 PM
Osler is excited to welcome this year’s cohort of students to the Osler Research Institute for Health Innovation as part of the 2025 Summer Student Research Program (SSRP). Over the next 15 weeks, 18 emerging researchers will work alongside Osler mentors and clinicians to build hands-on experience and contribute to real-world health research.
Please join us in welcoming the 2025 SSRP cohort.
2025 SSRP projects:
- Principal Investigator (PI): Hemant Shah, Academics Department, Assessing faculty...